5454 Main Street
Williamsville, NY

Prime retail space now available in the heart of the Village of Williamsville.

4,581 square feet of retail space is now available in the heart of the historic Village of Williamsville. Located in the Village's growing business and shopping district, 5454 Main Street is nestled among one-of-a-kind boutiques and national retailers including Talbots, Chico's, Calico Corners and Starbucks.

With Main Street exposure to 43,322 vehicles per day, and proximity to five of the top ten wealthiest zip codes in Western New York, this location represents an exceptional opportunity for a retailer looking to draw from one of the most affluent communities in the region. 5454 Main is also conveniently located just minutes from the NYS Thruway (I-90) and the Youngmann Highway (I-290).

  • 4,581 square feet now available.
  • Highly visible retail location in the heart of Williamsville's business and shopping district.
  • Outstanding demographics and high daily traffic count.
  • Will finish to tenant specifications.


Let our experienced leasing and design professionals show you the positive impact well located new retail space can have on your business and on your bottom line. For more information, please contact us at 716.633.2096 or leasing@iskalo.com.

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